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The OpenMS Proteomics Pipeline (TOPP) is a set of computational tools that can be chained together to tailor problem-specific analysis pipelines for HPLC-MS data. It transforms most of the OpenMS functionality into small command line tools that are the building blocks for more complex analysis pipelines. The functionality of the tools ranges from data preprocessing (file format conversion, baseline reduction, noise reduction, peak picking, map alignment,...) over quantitation (isotope-labeled and label-free) to identification (wrapper tools for Mascot, Sequest, InsPecT and OMSSA). TOPP is developed in the groups of Prof. Knut Reinert () at the Free University of Berlin and in the group of Prof. Kohlbacher () at the University of Tübingen. For more detailed information about the TOPP tools, see the TOPP (documentation ) of the latest release and the TOPP publication in the references. The OpenMS Proteomics Pipeline is free software released under the 3-clause BSD license.〔(readme ), (license.txt )〕 == References == * Sturm M, Bertsch A, Groepl C, Hildebrandt A, Hussong R, Lange E, Pfeifer N, Schulz-Trieglaff O, Zerck A, Reinert K, Kohlbacher O: OpenMS – An open-source software framework for mass spectrometry. ''BMC Bioinformatics'' 2008, 9:163.((fulltext )) * Kohlbacher O, Reinert K, Gröpl C, Lange E, Pfeifer N, Schulz-Trieglaff O, Sturm M: TOPP - the OpenMS proteomics pipeline. ''Bioinformatics'' 2007, 23(2):e191-7. ((fulltext )) 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「The OpenMS Proteomics Pipeline」の詳細全文を読む スポンサード リンク
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